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  • 產品名稱:SPTLC1抗原(重組蛋白)

  • 產品型號:1mg
  • 產品廠商:通蔚生物
  • 產品價格:3580
  • 產品庫存:35
  • 產品文檔:
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中文名稱: SPTLC1抗原(重組蛋白)

英文名稱: SPTLC1 Antigen (Recombinant Protein)

別     名:  HSN1; LBC1; LCB1; SPT1; SPTI; HSAN1

儲     存:  冷凍(-20℃)

相關類別: 抗原

概     述:

Fusion protein corresponding to C terminal 250 amino acids of human SPTLC1

技術規(guī)格

Full name:

serine palmitoyltransferase, long chain base subunit 1

Synonyms:

HSN1; LBC1; LCB1; SPT1; SPTI; HSAN1

Swissprot:

O15269

Gene Accession:

BC068537

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13.







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