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  • 產品名稱:CAPN6抗原(重組蛋白)

  • 產品型號:1mg
  • 產品廠商:通蔚生物
  • 產品價格:3580
  • 產品庫存:35
  • 產品文檔:
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CAPN6抗原(重組蛋白)打造了一支訓練有素的技術團隊,為抗體產品質量提供了強有力的保障,一直致力于研發(fā)生產高質量的科研試劑,為生命科學提供**的蛋白檢測相關產品,先進的實驗設備,強大的技術力量,誠信的服務態(tài)度是您實驗成果的保障!
詳情介紹:


中文名稱: CAPN6抗原(重組蛋白)

英文名稱: CAPN6 Antigen (Recombinant Protein)

儲     存:  冷凍(-20℃)

相關類別: 抗原

概     述

Fusion protein corresponding to a region derived from 26-343 amino acids of human CAPN6

技術規(guī)格

Full name:

calpain 6

Synonyms:

CANPX, CAPNX, CalpM, DJ914P14.1

Swissprot:

Q9Y6Q1

Gene Accession:

BC000730

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis.





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