中文名稱: ADD1 抗原(重組蛋白)
英文名稱: ADD1 Antigen (Recombinant Protein)
別 名: Alpha-adducin; ADDA
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述
Full length fusion protein
技術(shù)規(guī)格
Full name:
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Alpha-adducin
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Synonyms:
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ADDA
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Swissprot:
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P35611
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Gene Accession:
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BC013393
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Purity:
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>85%, as determined by Coomassie blue stained SDS-PAGE
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Expression system:
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Escherichia coli
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Tags:
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His tag C-Terminus, GST tag N-Terminus
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Background:
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Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
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