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  • 產品名稱:GMFG抗原(重組蛋白)

  • 產品型號:1mg
  • 產品廠商:通蔚生物
  • 產品價格:3580
  • 產品庫存:35
  • 產品文檔:
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詳情介紹:

中文名稱: GMFG抗原(重組蛋白)

英文名稱: GMFG Antigen (Recombinant Protein)

別     名:  GMF-GAMMA

儲     存:  冷凍(-20℃)

相關類別: 抗原

概     述

Full length fusion protein

技術規(guī)格

Full name:

glia maturation factor, gamma

Synonyms:

GMF-GAMMA

Swissprot:

O60234

Gene Accession:

BC080180

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Glia maturation factor, gamma, also known as GMFG, is a 142 amino acid protein that belongs to the GMF subfamily of the larger actin-binding protein ADF family. GMF-gamma is expressed predominantly in lung, heart and placenta. GMF-gamma is considered a candidate regulatory growth factor protein, mediating both paracrine and autocrine cell-cell interactions. GMF-gamma is phosphorylated at N-terminal serine, and its phosphorylation is enhanced by coexpression of dominant active Rac 1 and Cdc42. GMF-gamma expression is significantly increased in a cardiac ischemia/reperfusion model where inflammation and angiogenesis take place actively. As a regulator of actin-based cellular functions, GMF-gamma may provide a novel approach to modulate the pathophysiology of cardiovascular diseases. GMF-gamma is primarily found in proliferative and differentiative organs.





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